جستجوی مقالات مرتبط با کلیدواژه "بیماریهای قلبی عروقی" در نشریات گروه "پزشکی"

In recent years, plastic waste and residuals in different ecosystems have been introduced as serious challenges. Plastics with different chemical structures and derivatives are extensively applied for the packing of foods, pharmaceutical products, cosmetics, and the like. Due to distinct polymeric backbones, plastics are highly resistant to thermooxidative, irradiation degradation, and mechanical stress, resulting in inadequate recycling and accumulation in the environment. These features make plastics threatening pollutants for humans and other living organisms. Simultaneous application of plasticizers and other components during the production of plastics can increase these toxic effects.

Here, the content and data related to plastic particles toxicity on cardiovascular system indexed in PubMed, Scopus, and Web of Science.

Data have indicated that plastic nanoparticles/microparticles induce several pathological conditions following their entry into the body via cutaneous tissue, gastrointestinal ingestion, and inhalation. Plastic particles use different mechanisms to stimulate cytotoxicity and genotoxicity in several organs. The cardiovascular system and mainly endothelial cells are in close contact with circulating plastic particles and subsequent injuries. Endothelial cell cytotoxicity induced by plastic derivatives via different molecular mechanisms was discussed in this review article. The reduction of viability (either autophagy or apoptotic death), mitochondrial injury, oxidative stress, disruption of cell-to-cell integrity, and the like are the main underlying mechanisms in the presence of plastic particles.

These findings help us understand the vascular tissue injury induced by plastic nanoparticles and microparticles and develop preventive and therapeutic approaches.

Despite the fact that public awareness about diabetes control and cardiovascular diseases has increased, but still the main cause of morbidity and mortality in the community. For the treatment and control of diabetes and heart disease can be pharmacological and nonpharmacological methods used. The purpose of this review study is to introduce several risk factors in diabetic patients that increase the chances of cardiovascular involvement.

In this review study, Pubmed, ISI and Scopus databases were used to search for articles during the years 1979 to 2020, and the keywords of blood pressure, oxidative stress, obesity, dyslipidemia, endothelial function and inflammatory factors were used.

The worldwide prevalence of diabetes and the occurrence of serious and dangerous complications on the organs of the body, has made this disease a major health problem in all communities and is the main cause of cardiovascular disease. Our study showed that cardiovascular disease is the most common cause of death in diabetic patients. Factors associated with diabetes and cardiovascular disease include high blood pressure, oxidative stress, obesity, dyslipidemia, endothelial function, and inflammatory factors.

Diabetes is a major cause of cardiovascular disease. Cardiovascular disease is also the most common cause of death in diabetics.

Due to the frequency, prevalence, and specific nature of cardiovascular diseases in our country, and the multiplicity, variety, complexity, and high cost of diagnostic and therapeutic services and equipment, the possibility of inducing demand in this category of diseases is higher. Using the partial least squares approach, this study aimed to test the factors affecting the induced demand in cardiovascular diseases, and provide a model of the relationship between these factors.

This was a library study with a systematic review of 49 articles, and then a survey of 118 people selected via random sampling method. First, a list of factors, sub-factors and components related to induced demand was extracted using qualitative content analysis technique; and then, using analysis technique, the path of the fitting model and the final model were validated by completing a validated questionnaire by physicians, experts, staff, and clients of Shahid Chamran Heart Hospital in Isfahan, Iran, in 2019.

Results:

In this study, 5 main factors, 18 sub-factors, and 82 items were obtained. In fitting the measurement model, the combined reliability coefficient, cross validity, convergent, and divergent the results of test was acceptable, and in structural fit model, path coefficients were significant, except for “patients” coefficient, at the 95% confidence, the mean model determination coefficient was 0.822 (strong), and the predictive fit index, except for the characteristics of medical services, was greater than 0.02 (acceptable). The result of the overall fit test was 0.133, which indicated the desirability of the overall fit of the model. The validity of the final model was confirmed with 77% agreement of experts.

Based on the findings of this study, it is necessary to adopt an appropriate policy at the macro-level to reform the network structure and referral and strengthen information management, and at the executive level, to modify payment methods, change tariffs and franchises for services, and change insurance methods and coverage.

Cardiovascular diseases are one of the most common chronic illnesses. Despite the advancement in the management of heart failure, it still remains as one of the most important causes of mortality and morbidity. Anemia is a common finding in heart failure patients and decreases both life quality and bodily function in this group of patients. It is also related with high mortality and morbidity. The aim of the present study was to determine the ferritin levels in heart failure patients.

This cross-sectional study was conducted on heart failure patients admitted in Ganjavian Hospital, Ahvaz, Iran. Sampling was done by census method for three months duration (July-Sept 2019) and finally a total of 100 patients were recruited. Serum ferritin (ELISA), iron level and Total iron binding capacity (TIBC) was measured in all of the patients. Iron and TIBC were measured with Autoanalizer.

Of the 100 patients, 34% were females and 66% were males. Mean age was 65.21 yrs. 49 patients had severe decrease in EF , while 51 had moderate decrease in EF. Based on EF, t-test showed significant statistical difference in regard to age and ferritin between the two groups (p<0.05), while other variables did not show significant difference.Correlation coefficient of variables in regard to patientchr('39')s age with BUN and Creatinine (p<0.05), BUN with Creatinine and serum ferritin (p<0.001), sodium and serum iron (p<0.05), and ESR with TIBC and CRP (p<0.05) demonstrated positive correlation. While a negative correlation was observed in cases of serum sodium and potassium (p<0.001), ESR and serum iron (p<0.05), and TIBC and ferritin (p<0.001). No other significant correlation was found among other variables (p>0.05).

Results did not show significant relation between serum ferritin level with disease severity and complications. Thus, further studies are needed to prove the role of f ferritin as an independent risk factor in developing heart failure.

Due to controversies in different studies about the effects of L-arginine supplementation on athletic performance and cardiovascular risk factors, this study aimed to review the current evidence on the effects of L-arginine supplementation on athletic performance and cardiovascular risk factors.

This study was done to summarize findings from earlier evidence on the effect of L-arginine supplementation on the risk of cardiovascular disease. We searched in PubMed, Scopus and Google Scholar through 1975 till 2017 using the following keywords: cardiovascular OR athletic performance OR hypertension OR blood pressure OR sports performance OR lipid profile in combination with L-arginine OR arginine. After reviewing title and abstracts, all clinical trials and cross-sectional studies conducted on healthy people or those suffering from the disease were included.

In most studies, consumption of L-arginine supplementation improves athletic performance and body composition in athletes, although there are some contradictions in this field. Most studies confirmed the effect of L-arginine on decrease cardiovascular risk factors, and most of the work considered that this effects as a result of increased levels of nitric oxide (NO) in serum.

Most of the clinical trials indicated favorable effects of L-arginine supplementation on athletic performance and cardiovascular risk factors and taking this supplement at a dose of 2-5 grams per day has no side effects and promotes the health. Due to controversies in some study for giving high doses of this s

Type 2 diabetes is a common metabolic disorder accompanied by increased risk of cardiovascular diseases، along with increased morbidity and mortality. In recent years، epidemiological evidence and clinical studies have indicated that dietary polyphenols and phytochemical-rich foods have key role in prevention of cardiovascular diseases، especially coronary heart disease and myocardial infarction. The current review was conducted to investigate the mechanism of the effects of polyphenols in natural foods on prevention of diabetes-induced cardiovascular diseases.

“polyphenols”، “phenolic acids”، “anthocyanins”، “flavonoids”، and “lignans” in combination with “type 2 diabetes”، “insulin resistance”، “cardiovascular disease”، “endothelial dysfunction”، “oxidative stress”، “inflammation”، “lipid disorders”، and “hypertension” were used as key words for search in PubMed between 1990 and 2013. Cellular studies، animal models and clinical trials with appropriate design، and review article with high quality were used.

Dietary polyphenols have high potential to improve lipid profiles through decrease in digestion and ingestion of dietary fats، increase in turnover and excretion of cholesterol، reduction of synthesis of atherogenic apo lipoproteins، and inhibition of cholesterol and triglycerides synthesis. These compounds protect vascular endothelium against oxidative damages and inflammatory processes، improve function of vascular endothelium، modify the pathways related to platelets and coagulation، and even protect cardiac tissue and improve myocardial hemodynamics.

Higher consumption of foods containing polyphenols and using polyphenol-rich natural extract can be useful in decreasing the risk of development of cardiovascular diseases in type 2 diabetic patients.

Nasolacrimal There is a strong need for biomarkers to identify patients at risk for future cardiovascular events related with progressive atherosclerotic disease. Ideally, increasing knowledge of the mechanisms of atherosclerotic plaque destabilization should be translated in clinical practice. Systemic approaches are pursued to discover serum biomarkers that are applicable to define patients at risk for future cardiovascular events. Elevation in inflammatory markers, such as C-reactive protein, predicts outcomes of patients with acute coronary syndromes. Osteoprotegerin (OPG) protects the skeleton from excessive bone resorption by binding to receptor activator of nuclear factor-κB ligand (RANKL) and preventing it from binding to its receptor, receptor activator of nuclear factor-κB. Emerging evidence from in vitro studies, mouse genetics and clinical studies attributed to OPG an important role in vascular biology. But conflicting results have been obtained about association of serum level of OPG or RANKL with coronary artery disease (CAD). Based on their role in inflammation and matrix degradation and the fact that atherosclerotic plaque formation is an inflammatory process; we hypothesized that RANKL:OPG ratio could be a better biomarker for CAD.